Central Research Institute for Gastroenterology

All-Union Central Research Institute for Gastroenterology (CRIG) of the USSR Ministry of Health was established on the March, 25th, 1967 by the order of the Council of Ministers.

The Institute included 3 parts:

1. The Department of chronic hepatitides and portal hypertension organized in the Institute for Internal Medicine by its director A.L. Myasnikov, an academician of the USSR Academy of Medical Sciences. The Department consisted of 17 doctors and was run by A.S. Loginov, MD, Ph.D.

2. Research group led by V.Kh. Vasilenko, an academician of the USSR Academy of Medical Sciences, and run by him Department of Propedeutics of the First Moscow Medical Institute (MMI) (18 doctors).

3. The surgical team transferred from the Institute for Surgery of the USSR Ministry of Health (8 doctors).

V.Kh. Vasilenko was assigned to be the director of CRIG.  A.S. Loginov, D.Sc, Prof., became the Deputy Director in Research and the Head of Hepatopacreatobiliary diseases Department. Prof. N.O. Nikolayev (an academician B.V. Petrovskiy’s mentee) started to run the surgery department. CRIG had 300 beds. The Department of Propedeutics included three wards with 60 beds in each, and the Institute of Internal Medicine consisted of four wards with 30 beds in each. In fact, there has not been a true union of the three. The hepatology department remained a “stranger” in the First MMI. Finally, on August 27th, 1973, the Institute for Gastroenterology was separated from the Department of Propedeutics of the First MMI, reassigned to the Moscow Healthcare Committee (today – Moscow Healthcare Department) and expanded up to 550 beds. The Institute was transferred to 86, Shosse Entuziastov, where it occupied one laboratory and buildings two inpatients of the former city hospital No 58 and stayed there since.

Anatoly S. Loginov, D.Sc, Prof., was assigned for the position of the director of CRIG. He later became an academician of the USSR Academy of Medical Sciences.

A.S. Loginov was first to widely implement laparoscopy in clinical practice. Until then, there were a few attempts of laparoscopy application in the practice, mostly taken by surgeons. Loginov introduced laparoscopy to an internist practice as a diagnostic method in gastrointestinal diseases. He started performing laparoscopy in 1960 in the Hepatology department of the Institute for Internal Medicine. For the first time, he proposed using a colored photo in the diagnosis of liver diseases. In 1964-1969, he published several monographs on laparoscopy and an atlas of laparoscopic surgery and microphotos of liver biopsy tissue (he performed targeted liver biopsies). It is hard to overestimate the importance of laparoscopy implementation into clinical practice, especially into Hepatology, where diagnostic laparoscopy with targeted liver biopsy followed by the tissue examination has led to a breakthrough. Loginov’s contribution has become a driving factor of the laparoscopy broad use in surgery as well.

Hepatology was Loginov’s favorite area of gastroenterology. He ran the Hepatology department pro bono and remained the CRIG director for 33 years up until he passed away in 2000.

In February 2001 - July 2012, Leonid B.Lazebnik, D.Sc, Prof., was the director of CRIG.

In September 2012, this position was assigned to Igor E.Khatkov, D.Sc, Prof.

Currently, CRIG includes 540 beds. Yearly, 9500 inpatients and more than 30000 outpatients undergo treatment.

The major objective of CRIG is the fulfillment of target comprehensive research program “The improvement of diagnosis and treatment of gastrointestinal diseases”. Doctors and researchers in CRIG develop methods of regenerative medicine, study ways of using biotechnologies in the treatment of gastrointestinal diseases, maintain registries of patients with gastrointestinal disorders that need consistent follow up, and work on organ-sparing techniques for life-long treatment of such patients. They study epidemiology and aetiopathogenesis of gastrointestinal diseases, conduct studies on the pharmacoeconomic analysis of these diseases treatment.

Endoscopy as a diagnostic method has been broadly used in the Institute. In the early 1960s, doctors of CRIG implemented retrograde endoscopic cholangiopancreatography by physicians jointly with surgeons for both diagnostic and treatment purposes.

In 2003-2009, the first multicenter study “Epidemiology of gastroesophageal reflux disease in Russia” was conducted.

In 2008, standards “Diagnosis and treatment of acid-dependent diseases” were produced.

Surgeons in the Institute work in the tight collaboration with all non-surgical departments and labs.

The CRIG surgery department activity increased since the end of 2012 when the surgeons started to perform complex high-tech procedures.

Among others, the Institute is also an educational organization, as, in 2007, it acquired the license for postgraduate education and the right to issue state diplomas (accreditation No25, July 27th, 2009).

Currently, 29 residents and 5 Ph.D. students are undergoing their training in CRIG. Moreover, 120-140 doctors take complementary educational courses yearly.